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New drug may shield heart surgery patients from deadly complications

NCT ID NCT07594509

First seen May 26, 2026 · Last updated Jun 20, 2026 · Updated 5 times

Summary

This study tests whether the drug vericiguat can prevent serious heart and organ problems in people undergoing heart surgery. About 600 high-risk patients will receive either vericiguat plus standard care or standard care alone. The goal is to see if vericiguat reduces early complications like low cardiac output, heart injury, and major adverse events within a year.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The First Affiliated Hospital of Nanjing Medical University

    Nanjing, Jiangsu, 210029, China

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Vericiguat

What this could lead to

If it works, this could lead to a new standard treatment to prevent serious heart and organ damage after cardiovascular surgery.

What could go wrong

This trial hasn't started yet, and it's not a cure—it aims to reduce complications. Results may not apply to all surgery types or patients.

Conditions

The condition(s) this trial relates to.

cardiovascular disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.