Hernia surgery study seeks to uncover hidden inflammation risks
NCT ID NCT07422584
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at how much tension is placed on the abdominal wall during hernia repair surgery and how that affects the body's inflammation and immune response. Researchers will measure inflammatory markers in blood and fluid from the surgery site in 25 adults undergoing hernia repair. The goal is to understand the body's reaction to different levels of tension, which could lead to better surgical techniques and fewer complications.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this study could help surgeons understand how to reduce inflammation and complications after hernia repair.
- What could go wrong
- This is a small, early observational study with only 25 participants, so findings may not apply to all patients. It does not test a new treatment.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
About 25 people
The number the study aims to enrol. It can still change while the study runs.
- Started
-
Feb 2026
- Expected to finish
-
Mar 2027
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Participants will include adult patients undergoing elective major abdominal wall reconstruction at Northwestern Memorial Hospital. Patients with large ventral hernias requiring component separation and anticipated primary fascial closure will be eligible.
- Ages
-
18 years and older
- Sex
-
Anyone
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Surgical Participants * Adults aged 18 years or older * Scheduled to undergo open retromuscular ventral hernia repair * Able to provide written informed consent Healthy Control Participants * Adults aged 18 years or older * No known inflammatory, autoimmune, or immunologic disease * Able to provide written informed consent Exclusion Criteria: * Emergent or urgent cases * Pregnancy * Chronic systemic steroid use or immunosuppressive therapy * Active infection at the time of enrollment * Known autoimmune or inflammatory disease * End-stage organ failure * Abdominal surgery within the preceding 60 days
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Incisional ventral hernia are added.
Genom att skicka in godkänner du våra Användarvillkor
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
-
The places running it
1 site. The list below names each one and where it is.
-
The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
-
A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
-
Northwestern Memorial Hospital
RECRUITINGChicago, Illinois, 60611, United States