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Which ventilator mode saves more lives? huge ICU study aims to find out

NCT ID NCT07313956

First seen Jan 05, 2026 · Last updated May 24, 2026 · Updated 23 times

Summary

This study looks at whether the type of breathing machine setting used in the ICU affects how well patients recover. Researchers will switch the ventilator mode used in entire ICUs every two months and track survival and time off the machine. About 4,785 adults on breathing machines will take part. The goal is to find out which mode helps patients live longer and breathe on their own sooner.

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Contacts and locations

Locations

  • Rush University Medical Center

    Chicago, Illinois, 60612, United States

  • The Johns Hopkins Hospital

    Baltimore, Maryland, 21224, United States

  • Vanderbilt University Medical Center

    Nashville, Tennessee, 37232, United States

  • Wake Forest University Health Sciences

    Winston-Salem, North Carolina, 27109, United States

Conditions

Explore the condition pages connected to this study.