New device aims to free ICU patients from ventilators faster
NCT ID NCT05759013
First seen Nov 12, 2025 · Last updated May 23, 2026 · Updated 19 times
Summary
This study tests a device called VentFree that uses mild electrical pulses to strengthen breathing muscles in critically ill patients on ventilators. The goal is to see if it helps them wean off the breathing machine sooner. About 272 adults who have been on a ventilator for 1 to 4 days will receive either the real device or a sham (fake) treatment. The main measure is how quickly they can breathe without help for at least 7 days.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Baylor College of Medicine
Houston, Texas, 77030, United States
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Canisius Wilhelmina Ziekenhuis (CWZ)
Nijmegen, Netherlands
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Centre Hospitalier Universitaire d'Angers
Angers, 49933, France
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Edward Hines, Jr. VA Hospital
Hines, Illinois, 60141, United States
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Erasmus Medical Center
Rotterdam, Netherlands
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Houston Methodist Hospital
Houston, Texas, 77030, United States
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Hôpital Saint Joseph Saint Luc
Lyon, 69365, France
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Jeroen Bosch Ziekenhuis (JBZ)
's-Hertogenbosch, Netherlands
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Loyola University
Maywood, Illinois, 60153, United States
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MD Anderson Cancer Center
Houston, Texas, 077030, United States
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Memorial Hermann
Houston, Texas, 77030, United States
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MemorialCare Long Beach Medical Center
Long Beach, California, 90807, United States
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Monash Medical Centre
Clayton, Australia
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Nepean Hospital
Kingswood, Australia
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Pitié-Salpêtrière University Hospital
Paris, France
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Prince of Wales Hospital
Randwick, Australia
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Providence Regional Medical Center
Everett, Washington, 98201, United States
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Radboud University Medical Center
Nijmegen, Netherlands
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Royal North Shore Hospital
St Leonards, Australia
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St. George Hospital
Kogarah, Australia
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Tufts Medical Center
Boston, Massachusetts, 02111, United States
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University of Cincinnati
Cincinnati, Ohio, 45221, United States
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University of Florida College of Medicine - Jacksonville
Jacksonville, Florida, 32206, United States
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University of Louisville
Louisville, Kentucky, 40202, United States
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University of Pittsburgh
Pittsburgh, Pennsylvania, 15260, United States
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Vanderbilt University Medical Center
Nashville, Tennessee, 37232, United States
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Weill Cornell Medicine / New York Presbyterian Hospital
New York, New York, 10065, United States
Conditions
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