Gentler combo could rival chemo for tough blood cancer
NCT ID NCT04801797
First seen Nov 15, 2025 · Last updated May 24, 2026 · Updated 26 times
Summary
This study tests whether a combination of two drugs, venetoclax and azacitidine, works as well as or better than standard chemotherapy for adults newly diagnosed with acute myeloid leukemia (AML). About 172 participants will be randomly assigned to receive either the new combo or standard chemo. The main goal is to see which approach helps patients live longer without the cancer getting worse or coming back.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Atrium Health Levine Cancer Institute
Charlotte, North Carolina, 28204, United States
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Beth Israel Deaconess Medical Center
Boston, Massachusetts, 02215, United States
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City of Hope
Duarte, California, 91010, United States
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Dana-Farber Cancer Institute
Boston, Massachusetts, 02215, United States
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Massachusetts General Hospital Cancer Center
Boston, Massachusetts, 02114, United States
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Ohio State University Medical Center
Columbus, Ohio, 43210, United States
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Stanford Cancer Center
Palo Alto, California, 94304, United States
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University of California - Davis
Sacramento, California, 95817, United States
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University of Pennsylvania
Philadelphia, Pennsylvania, 19104, United States
Conditions
Explore the condition pages connected to this study.