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Drug combo may help radioactive iodine work better in tough thyroid cancers

NCT ID NCT06440850

First seen Jan 11, 2026 · Last updated May 21, 2026 · Updated 22 times

Summary

This study tests whether two targeted drugs, vemurafenib and cobimetinib, can make thyroid cancer cells more responsive to radioactive iodine therapy. About 21 adults with a specific gene mutation (BRAF V600E) and high-risk thyroid cancer will receive the drug combo before their first radioactive iodine treatment. The goal is to see if this approach leads to better cancer control with fewer side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • City of Hope Medical Center

    RECRUITING

    Duarte, California, 91010, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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