New drug combo could make radioactive iodine work better for tough thyroid cancers

NCT ID NCT06440850

First seen Jan 11, 2026 · Last updated May 14, 2026 · Updated 18 times

Summary

This study tests whether two targeted drugs, vemurafenib and cobimetinib, can help high-risk thyroid cancer patients respond better to standard radioactive iodine therapy. The drugs block a faulty protein that drives cancer growth, potentially making cancer cells more receptive to radiation. About 21 adults with a specific BRAF gene mutation will be enrolled and followed for around 14 months.

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Contacts and locations

Locations

  • City of Hope Medical Center

    RECRUITING

    Duarte, California, 91010, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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