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New heart valve replacement offers hope for severe leakage

NCT ID NCT05848284

First seen Jan 30, 2026 · Last updated May 21, 2026 · Updated 14 times

Summary

This study tests a new device called the VDyne System to replace the tricuspid valve in 30 people with severe tricuspid regurgitation (leaky valve). The goal is to see if the device is safe and can improve symptoms, exercise ability, and quality of life. Participants must have severe symptoms despite medical therapy and be approved by a heart team.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Ascension St. Thomas

    RECRUITING

    Nashville, Tennessee, 37205, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Cedars-Sinai Medical Center

    RECRUITING

    Los Angeles, California, 90048, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Columbia University Medical Center/NYPH

    RECRUITING

    New York, New York, 10032, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Henry Ford Hospital

    RECRUITING

    Detriot, Michigan, 48208, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Mayo Clinic - Rochester

    RECRUITING

    Rochester, Minnesota, 55905, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Medical University of South Carolina

    RECRUITING

    Charleston, South Carolina, 29425, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Minneapolis Heart Institute Foundation

    RECRUITING

    Minneapolis, Minnesota, 55407, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Montefiore Medical Center

    RECRUITING

    The Bronx, New York, 10467, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Oregon Health and Science Unversity

    RECRUITING

    Portland, Oregon, 97239, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Québec-Université Laval (IUCPQ-ULaval)

    RECRUITING

    Québec, Quebec, G1V 4G5, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • The Christ Hospital

    RECRUITING

    Cincinnati, Ohio, 45219, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.