Experimental tumor injection shows promise in early cancer trial
NCT ID NCT05901285
First seen Nov 26, 2025 · Last updated May 21, 2026 · Updated 18 times
Summary
This early-phase study tests an experimental drug called VAX014, which is injected directly into tumors to kill cancer cells. The trial includes up to 48 adults with advanced solid tumors that have not responded to standard treatments. Researchers are checking safety, the best dose, and whether combining VAX014 with an immunotherapy drug (nivolumab or pembrolizumab) can shrink tumors.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Atlantic Health System
RECRUITINGMorristown, New Jersey, 07960, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Cleveland Clinic
RECRUITINGCleveland, Ohio, 44195, United States
Contact Phone: •••-•••-••••
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Dana Farber Cancer Institute
RECRUITINGBoston, Massachusetts, 02215, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Dartmouth Cancer Center
RECRUITINGLebanon, New Hampshire, 03756, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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George Washington University
RECRUITINGWashington D.C., District of Columbia, 20052, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Sarah Cannon Research Institute at HealthONE
RECRUITINGDenver, Colorado, 80218, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Arizona Cancer Center
RECRUITINGTucson, Arizona, 85719, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
Explore the condition pages connected to this study.