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Surgery shock: common blood pressure drug may be better than another, study finds

NCT ID NCT04789330

First seen Jan 11, 2026 · Last updated May 23, 2026 · Updated 20 times

Summary

This study tested two drugs, norepinephrine and phenylephrine, to treat low blood pressure during major surgery under general anesthesia. Over 3,600 adults having long surgeries (over 2 hours) took part. The goal was to see which drug leads to fewer serious problems like kidney injury or death within 30 days after surgery. Results will help doctors choose the best option for safer surgery.

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Contacts and locations

Locations

  • Ronald Reagan UCLA Medical Center

    Los Angeles, California, 90095, United States

  • UCSF Medical Center at Mission Bay

    San Francisco, California, 94158, United States

  • UCSF Medical Center at Mount Zion

    San Francisco, California, 94115, United States

  • UCSF Medical Center at Parnassus

    San Francisco, California, 94143, United States

  • Zuckerberg San Francisco General Hospital

    San Francisco, California, 94110, United States

Conditions

Explore the condition pages connected to this study.