Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

Sitting too much may harm your blood vessels – study investigates why

NCT ID NCT04872998

Knowledge-focused Sponsor: University of Utah Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at how reducing daily steps by about 70% affects blood vessel function and muscle health in older adults. Researchers measured blood flow in arm and leg arteries to understand the role of oxidative stress. The goal is to learn why inactivity leads to muscle loss and poor recovery, especially after surgery or hospitalization.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this research could point toward ways to prevent or reverse blood vessel and muscle damage caused by inactivity.
What could go wrong
This is a small, early-stage observational study with only 14 participants, so findings may not apply broadly. It does not test a treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

14 people

The number who actually took part.

Started

Mar 2019

Finished

Mar 2021

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Individuals who have recently undergone surgery or injury requiring inactivity Exclusion Criteria: * Cardiac abnormalities considered exclusionary by the study physician (congestive heart failure, coronary artery disease, right-to-left shunt) * Uncontrolled endocrine or metabolic disease * Glomerular filtration rate \< 45 mL/min/1.73 m\^2 or evidence of kidney disease or failure * Vascular disease or risk factors of peripheral atherosclerosis * Risk of deep vein thrombosis including family history of thrombophilia, pulmonary emboli, deep vein thrombosis * Use of anticoagulant therapy * Elevated systolic pressure \> 180 or a diastolic blood pressure \> 110 * Implanted electronic devices such as pacemakers, infusion pumps, stimulators * Cancer or history of successfully treated cancer (less than 1 year) other than basal cell carcinoma * Currently on a weight-loss diet or body mass index \> 35 kg/m\^2 * Inability to abstain from smoking for duration of study * History of \> 20 pack per year smoking * Positive for human immunodeficiency virus, hepatitis B or hepatitis C * Recent anabolic or corticosteroids use (within 3 months) * Subjects with hemoglobin or hematocrit lower than accepted lab values * Agitation/aggression disorder * History of stroke with motor disability * Recent history (\< 12 months) of gastrointestinal bleed * Depression diagnosis * Alcohol or drug abuse * Liver disease (AST/ALT 2 times above the normal limit, hyperbilirubinemia) * Respiratory disease (acute upper respiratory infection, history of chronic lung disease with resting oxygen saturation \< 97% on room air) * Pregnancy

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Aging are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

muscular atrophy skeletal muscle disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Aging Skeletal muscle Vascular endothelium

Contacts and locations

Locations

  • VA Medical Center Building

    Salt Lake City, Utah, 84148, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.