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Antibiotic trial for rare liver disease halted early

NCT ID NCT03710122

First seen Apr 22, 2026 · Last updated May 21, 2026 · Updated 6 times

Summary

This study tested if the antibiotic vancomycin could safely improve liver health in adults with primary sclerosing cholangitis (PSC), a rare liver disease. About 102 participants were planned, but the trial was stopped early. The main goal was to see if vancomycin could lower alkaline phosphatase, a marker of liver damage, compared to a placebo.

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Contacts and locations

Locations

  • Arizona State University

    Tempe, Arizona, 85281, United States

  • Mayo Clinic Arizona

    Phoenix, Arizona, 85259, United States

  • Mayo Clinic Florida

    Jacksonville, Florida, 32224, United States

  • Mayo Clinic Rochester

    Rochester, Minnesota, 55905, United States

Conditions

Explore the condition pages connected to this study.