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Bone injection may beat IV for preventing amputation infections in diabetics

NCT ID NCT07338773

First seen Jan 19, 2026 · Last updated Jun 18, 2026 · Updated 23 times

Summary

This study tests whether giving the antibiotic vancomycin directly into the bone (intraosseous) during diabetic foot amputation works better than the standard IV method to prevent surgical site infections. It includes 40 adults with diabetes who need a below-knee amputation. Researchers will measure antibiotic levels at the wound and track infections, kidney function, and need for repeat surgeries over 90 days.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Basaksehir Cam ve Sakura City Hospital

    RECRUITING

    Istanbul, Istanbul, 34010, Turkey (Türkiye)

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

Diabetic Foot

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.