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Healthy volunteers help test vamorolone's hidden salt switch

NCT ID NCT06649409

First seen Nov 01, 2025 · Last updated May 22, 2026 · Updated 37 times

Summary

This completed Phase 1 study in 30 healthy adults tested whether the drug vamorolone can block the mineralocorticoid receptor, which helps control salt and water balance. Participants received vamorolone, a comparison drug, or no treatment, and researchers measured urine sodium and potassium levels. The study was not designed to treat any disease, but to gather basic knowledge about how vamorolone works in the body.

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Contacts and locations

Locations

  • Nuvisan GmbH

    Neu-Ulm, 89231, Germany

Conditions

Explore the condition pages connected to this study.