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VR headset could help stroke survivors relearn daily tasks at home
NCT ID NCT07450586
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether a virtual reality (VR) home exercise program can help stroke survivors improve arm and hand function. Forty-eight adults who had a stroke at least 3 months ago will either use a VR headset to practice daily activities at home or receive standard therapy. The goal is to see if VR therapy is as good or better than usual care for regaining movement.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Virtual reality headset (Meta Quest) with software for practicing daily living activities
- What this could lead to
- If it works, this could provide a convenient, at-home therapy option to help stroke survivors regain arm and hand function.
- What could go wrong
- This is a small, early-phase trial with only 48 participants. The VR program may not be more effective than standard therapy, and some people may have difficulty using the technology.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 48 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jun 2026
An estimate. Start dates often move.
- Expected to finish
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Jul 2027
An estimate. End dates often move.
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Criteria for inclusion: 1. Participant has had a right or left hemispheric stroke affecting normal hand function. 2. At least 3 months have passed since the last stroke. 3. Participant has sufficient active finger flexion at the MCP joint in at least one finger to be detected by visual observation by a study therapist. 4. Participant has visual acuity with corrective lenses of 20/50 or better. 5. Participant must have active movement against gravity of at least 30 degrees shoulder flexion, 45 degrees elbow flexion, elbow extension to within 30 degrees of full extension, and 15 degrees shoulder internal and external rotation. 6. In the opinion of a study therapist, participant can independently and safely use the system at home or has an at-home caregiver who is willing and able to assist. 7. In the opinion of a study therapist, participant has a suitable and safe space in their home for using the VALOR system. 8. Participant is willing and able to provide informed consent. Criteria for exclusion: 1. Withholding or withdrawal of consent by the participant. 2. Inability to understand and follow verbal directions. 3. Determination by the Principal Investigator that participation would result in overexertion or significant discomfort or pain. 4. A psychological diagnosis that in the determination of the Principal Investigator could significantly impact subject's participation or that could be aggravated by study participation (Principal Investigator will consult with candidate's personal physician as appropriate). 5. Determination by the Principal Investigator that participation would result in significant agitation or elevated stress. 6. Visual field deficit in either eye that impairs the ability to view the VR display. 7. Significant contractures of the muscles, joints, tendons, ligaments, or skin that restrict normal upper extremity movement. 8. More than mild tone/spasticity (measured on modified Ashworth, 5-point scale); 9. Severe pre-stroke co-morbidities, such as cardiovascular, neurological, orthopedic, or rheumatoid impairments before stroke that may interfere with task performance. 10. Severe sensory deficits from the involved UE; or 11. Hemispatial neglect that impairs the ability to process and perceive visual stimuli provided through the VR display. As the system will be adaptable to a wide range of hand dexterity, no restriction will be made for fine control of digits. Patients will not be excluded due to inability to use the VR headset. If at any time the study therapist, in consultation with the Duke PI, determines the patient is not tolerating VR headset use, the patient will be given the option to use a non-immersive version of the VALOR system which employs a TV monitor and depth sensor in lieu of the headset. Please see Potential Risks section for additional details on controls and mitigations for potential cyber sickness.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Duke University
Durham, North Carolina, 27705, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Moving patterns may help stroke survivors read faster
- Vibrating wearables put stroke walking to the test
- Robot plus electrical stimulation aims to rebuild arm movement after stroke
- Can a checklist and heart monitor stop repeat strokes?
- Heart hole or stroke trigger? global registry tracks who gets closure and what happens next