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New tool could help doctors predict recovery after pulmonary embolism

NCT ID NCT05568927

Knowledge-focused Sponsor: University of California, San Diego Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a step-by-step method called SEARCH to better classify what happens to people long after a pulmonary embolism (a blood clot in the lungs). Researchers looked at 150 adults to see if the method reliably identifies different outcomes, from full recovery to chronic conditions. The goal is to improve follow-up care and make it easier to use these outcomes in future research.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could give doctors a reliable, cost-effective way to identify different long-term outcomes after a pulmonary embolism, leading to better follow-up care.
What could go wrong
This is an observational study to validate a diagnostic algorithm, not a treatment trial. It is small (150 participants) and completed, so results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

150 people

The number who actually took part.

Started

Nov 2022

Finished

Jun 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study will recruit consecutive patients who, during the study period, underwent the SEARCH algorithm at one of the UCAPE network of outpatient pulmonary embolism clinics (UC San Diego, UC Irvine, UCLA Harbor, UCLA, UC Riverside, UC Davis, UC San Francisco or UCSF Fresno) three months or more after the occurrence of acute pulmonary embolism or any risk type.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * age 18 years or greater * objective evidence of acute pulmonary thrombo-embolism at least six months before the evaluation * anticipated survival for at least three months * a diagnostic endpoint in the SEARCH algorithm has been reached. Exclusion Criteria: ● Cases in which the clinical presentations contain insufficient interpretable data to permit evaluation of SEARCH criteria, as described in the Study Design section, will be excluded from the analysis.

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Conditions

The condition(s) this trial relates to.

chronic thromboembolic pulmonary hypertension pulmonary embolism

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Chronic thromboembolic pulmonary hypertension Pulmonary embolism

Contacts and locations

Locations

  • University Hospital, Riverside

    Moreno Valley, California, 92555, United States

  • University of California, Davis

    Sacramento, California, 95817, United States

  • University of California, Irvine

    Irvine, California, 92868, United States

  • University of California, Los Angeles

    Los Angeles, California, 90095, United States

  • University of California, Los Angeles - Harbor

    Torrance, California, 90502, United States

  • University of California, San Diego

    San Diego, California, 92103, United States

  • University of California, San Francisco

    San Francisco, California, 94143, United States

  • University of California, San Francisco-Fresno

    Fresno, California, 93701, United States

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