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Ear-Zap device shows promise for arthritis hand pain

NCT ID NCT04520516

First seen Oct 31, 2025 · Last updated Jun 09, 2026 · Updated 38 times

Summary

This study tested a device that sends mild electrical pulses to the ear to stimulate the vagus nerve, aiming to reduce pain and inflammation in people with erosive hand osteoarthritis, a painful and hard-to-treat arthritis. 148 adults with this condition used either the active device or a sham (inactive) device for 12 weeks. The main goal was to see if the active device reduced hand pain more than the sham.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Service de Rhumatologie - Hôpital Saint Antoine

    Paris, 75012, France

Conditions

The condition(s) this trial relates to.

Musculoskeletal Pain osteoarthritis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.