Tiny bacteria, big impact: could vaginal microbes determine surgical success?
NCT ID NCT02890498
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether the types of bacteria living in the vagina influence how well women recover after surgery for pelvic organ prolapse using a vaginal mesh. Researchers will analyze stored samples from 41 women who had this surgery, comparing those who had complications with those who did not. The goal is to see if certain bacterial patterns are linked to better or worse outcomes, which could one day help personalize surgical care.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this research could help doctors predict and prevent complications from vaginal mesh surgery, improving outcomes for women with pelvic organ prolapse.
- What could go wrong
- This is a small, retrospective analysis, so findings may not apply to all patients. It only looks at bacteria, not other factors that might influence recovery.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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41 people
The number who actually took part.
- Started
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Dec 2015
- Finished
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Dec 2017
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Females aged 18 and over who have consented for vaginal mesh surgery for pelvic organ prolapse at the Nîmes University Hospital, France
- Ages
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18 years and older
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Females aged 18 and over who have consented for vaginal mesh surgery for pelvic organ prolapse at the the Nîmes University Hospital, France Exclusion Criteria: * Pregnant or breast feeding * Unwilling or unable to complete questionnaire or give valid consent.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
CHU de Nîmes
Nîmes, 30029, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can strength training steady the walk and strengthen the pelvic floor after menopause?
- Can a biological mesh improve pelvic floor surgery?
- Can targeted exercises ease mild pelvic organ prolapse without surgery?
- AI may predict which pelvic floor therapy works best
- Can a small pressure drop make prolapse surgery less painful?
- Could a simple surgical step make hysterectomies safer?