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Scientists investigate why vaginal estrogen works for only half of women with recurrent UTIs

NCT ID NCT05551949

First seen Nov 01, 2025 · Last updated Apr 30, 2026 · Updated 22 times

Summary

This study looked at 27 postmenopausal women with frequent urinary tract infections (UTIs) to understand why vaginal estrogen therapy prevents UTIs in only about half of them. Researchers examined changes in vaginal and bladder bacteria and immune responses before and after treatment. The goal is to use these findings to develop better UTI prevention strategies for the future.

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Contacts and locations

Locations

  • Johns Hopkins Bayview Medical Center

    Baltimore, Maryland, 21224, United States

Conditions

Explore the condition pages connected to this study.