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New study aims to decode dizzy spells that could signal a stroke

NCT ID NCT07421973

Knowledge-focused Sponsor: University of Sao Paulo General Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study will follow 400 people who come to the emergency room with sudden vertigo or dizziness that might be caused by a mini-stroke in the back of the brain. Researchers will track their symptoms, treatments, and outcomes over a year to learn how to better diagnose and manage these episodes. The goal is to improve care and reduce the risk of future strokes.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could help doctors better identify which cases of vertigo or dizziness are due to a mini-stroke, leading to faster and more accurate treatment.
What could go wrong
This is an observational study, not a treatment trial, so it won't directly test a new therapy. Results may not change practice immediately and depend on careful follow-up of participants.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 400 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

May 2026

An estimate. Start dates often move.

Expected to finish

Oct 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adults presenting with acute or transient episodes of vertigo, dizziness, or unsteadiness that suggest vertebrobasilar transient neurological attacks will be evaluated in emergency departments or outpatient neurotology/neurology settings. Participants will be prospectively enrolled based on predefined clinical criteria and followed longitudinally to assess diagnostic confirmation, clinical characteristics, treatment responses, and prognostic outcomes.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Episodic acute vertigo, dizziness or unsteadiness transient or in evolution, therefore, lasting \<24 h * Such an episode may be isolated or associated with one or more of the following: 1. focal central neurological symptoms or severe postural instability; 2. new-onset, moderate-to-severe craniocervical pain; or 3. symptoms that are not better accounted for by another disease or disorder. Exclusion Criteria: * Patients who present with findings of acute hemorrhage or ischemia on the cranial magnetic resonance imaging (MRI), including diffusion-weighted MRI (DWI-MRI) at recruitment; * Patients who also fulfill the diagnostic criteria for other neurotological diseases that may present acute or recurrent transient dizziness/Vertigo (Unilateral Vestibulopathy; benign paroxysmal positional vertigo; Meniére's disease; Vestibular Migraine; Vestibular Paroxysmia; Persistente Postural-Perceptual Dizziness; and Postural Hypotension; * Patients whose symptoms last more than 24 hours or who have evidence of sequelae during follow-up; * Patients with contraindications to any of the therapeutic options proposed by this study method; * Patients who have other symptoms during the follow-up that suggest another etiology of dizziness or vertigo; * Patients who do not complete the entire evaluation; * Patients who refuse to sign the informed consent form.

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Conditions

The condition(s) this trial relates to.

Dizziness Emergencies transient ischemic attack vertebrobasilar insufficiency Vertigo

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Dizziness Tia (transient ischemic attack) Transient neurologic symptoms Vertigo

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Hospital das Clínicas - University of São Paulo

    São Paulo, São Paulo, 05403900, Brazil

More trials for these conditions

Other studies related to the condition(s) this trial covers.