Could a stick of gum soothe a spinning world?
NCT ID NCT07749573
First seen Aug 06, 2026 · Last updated Aug 07, 2026 · Updated 1 time
Summary
This trial tests whether chewing sugar-free gum for 20 minutes, alongside standard intravenous medication, can reduce dizziness and nausea in adults with a common inner-ear condition called posterior canal BPPV. Participants are randomly assigned to either chew gum or receive standard treatment alone, with symptom severity measured before and after. The idea is that chewing may stimulate nerve pathways that help calm the vestibular system, potentially offering a simple, drug-free boost to standard care.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Chewing gum (sugar-free, mint-flavored) added to standard intravenous dimenhydrinate treatment
- What this could lead to
- If chewing gum helps, it could offer a simple, drug-free way to ease dizziness and nausea during BPPV attacks, potentially reducing reliance on sedating medications.
- What could go wrong
- This is a small, early-stage trial, and the effect may be modest or not clinically significant. Chewing gum might not work for everyone, and the study only measures short-term symptom changes.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 88 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Sep 2026
An estimate. Start dates often move.
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Aged 18-65 years * Duration of dizziness complaint less than 24 hours * Posterior canal BPPV diagnosis confirmed by the emergency physician via the Dix-Hallpike test * Intravenous administration of 50 mg dimenhydrinate in 100 cc 0.9% NaCl initiated by the responsible emergency physician * Symptomatic dizziness with VAS ≥ 4 * Alert, cooperative, and able to chew gum * Willingness to participate and provision of written informed consent Exclusion Criteria: * Findings suggestive of central vertigo (vertical nystagmus, diplopia, ataxia, hemiparesis, focal neurological deficit, etc.) * Pregnancy * Known gum intolerance, history of allergy to gum or its excipients, temporomandibular joint dysfunction, significant tooth loss, use of dentures or removable prosthetics that would prevent chewing * Altered level of consciousness * Central pathology detected on investigations performed during the visit * Hemodynamic and/or respiratory instability * Diagnosis other than posterior canal BPPV as the cause of vertigo * Treatment other than pharmacological therapy planned or already administered by the responsible emergency physician * Active vomiting at the time of enrollment * Severe dizziness with VAS ≥ 8 (excluded due to high likelihood of requiring additional treatment, risk of protocol deviation, and safety concerns regarding gum chewing) * Patients who initially consented but subsequently wish to withdraw from the study
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Ankara Atatürk Sanatorium Training and Research Hospital
Ankara, Turkey (Türkiye)
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