Digital care plans after kidney injury could save lives
NCT ID NCT05806645
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether a personalized digital care plan, given at hospital discharge, can reduce serious health problems after acute kidney injury (AKI). About 6,000 adults who had AKI in hospital will be randomly assigned to receive either the tailored plan or usual care. The plan includes education, medication guidance, and follow-up lab tests, all delivered through Alberta's electronic health record system.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- personalized digital care plan
- What this could lead to
- If it works, this could improve outcomes for people leaving hospital after acute kidney injury, reducing the risk of death, kidney failure, and heart problems.
- What could go wrong
- This is a large pragmatic trial, but the intervention is a digital care plan, not a drug. Success depends on how well it is implemented and followed by patients and doctors.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 6,046 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Feb 2025
- Expected to finish
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Sep 2029
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: (all of) * Age ≥ 18 years old * Hospitalized at site using AHS EHR * Acute Kidney Injury (Stage 1-3) identified in hospital per KDIGO guideline criteria Exclusion Criteria: (any of) * Pre-hospitalization advanced CKD: eGFR\<30 mL/min/1.73m2 * Pre-hospitalization dialysis * Very low risk (\<1% risk) of advanced CKD * Non-Alberta resident * Palliative goals of care * Enrolled in the UPTAKE VC Trial * Admitted under a nephrologist at time of discharge * Dialysis on at least 2 days in the last week prior to discharge * Receiving apheresis * Kidney transplant recipient * Kidney transplant donor * Diagnosis of Glomerulonephritis * Cirrhosis AND complication of cirrhosis in medical history or active problem list (ascites, varices, hepatic encephalopathy, hepatorenal syndrome)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
2 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Foothills Medical Centre
RECRUITINGCalgary, Alberta, Canada
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University of Alberta Hospital
RECRUITINGEdmonton, Alberta, Canada
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- Can watching kidney oxygen during liver surgery keep kidneys safe?