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Which exercise burns fat better: upper or lower body?

NCT ID NCT07658261

Knowledge-focused Sponsor: Arya Habibi Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how upper body versus lower body combined strength and endurance training affects two key proteins in overweight and obese men: myostatin, which regulates muscle growth, and hormone-sensitive lipase, which helps break down fat. Thirty-six men were split into three groups: upper body training, lower body training, or no exercise. The goal is to see if focusing on different body parts changes how these proteins respond, which could inform better exercise recommendations.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
combined resistance and aerobic training
What this could lead to
If successful, this could help tailor exercise programs to better target muscle growth and fat metabolism in overweight individuals.
What could go wrong
This is a small, early-stage study with only 36 participants, so results may not apply to everyone. It measures biological markers, not long-term health outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

36 people

The number who actually took part.

Started

May 2024

Finished

Dec 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 to 45 years

Sex

Male participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Male participants aged 20 to 45 years. * Body mass index (BMI) ≥25 kg/m². * Overweight or obese status. * No participation in regular resistance or aerobic exercise during the previous 6 months. * Willingness to participate and provide written informed consent. Exclusion Criteria: * Presence of metabolic diseases, including diabetes mellitus. * Presence of cardiovascular or respiratory diseases. * Musculoskeletal or joint injuries that could interfere with exercise participation. * Use of anti-obesity medications. * Use of anabolic steroids, sports supplements, or fat-burning supplements. * Regular alcohol consumption or tobacco use. * Absence from more than two training sessions during the intervention period. * Withdrawal of consent or unwillingness to continue participation.

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Conditions

The condition(s) this trial relates to.

Obesity obesity disorder Overweight

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Obesity (bmi>30) Overweight (bmi > 25)

Contacts and locations

Locations

  • Faculty of Sports and Health Sciences of the University of Tehran

    Tehran, Tehran Province, Iran

More trials for these conditions

Other studies related to the condition(s) this trial covers.