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Could training one limb at a time boost heart health better than both?

NCT ID NCT07751445

Disease control Sponsor: Hacettepe University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 07, 2026 · Last updated Aug 07, 2026

Summary

This study tests whether doing strength exercises one limb at a time (unilateral) or both limbs together (bilateral) makes a bigger difference in heart rate variability, muscle strength, and daily function for adults with high blood pressure. Adults aged 40-75 with hypertension will be randomly placed into one of three groups: unilateral training, bilateral training, or a control group. Both training groups will do supervised resistance exercises twice a week for 12 weeks. The goal is to see which approach better supports heart health and physical performance, potentially guiding safer and more personalized exercise advice.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Unilateral or bilateral resistance training (supervised exercise program)
What this could lead to
If one training style proves better, it could lead to more effective exercise prescriptions for managing blood pressure and improving heart health in people with hypertension.
What could go wrong
This is a small, early-stage trial, so results may not apply to everyone. Exercise is generally safe, but there is a risk of injury or strain, and the benefits may not be dramatic.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 54 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jun 2026

Expected to finish

Oct 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

40 to 75 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 40 to 75 years. * Physician-confirmed diagnosis of hypertension. * Medically stable and able to safely participate in a supervised resistance training program. * Able to understand the study procedures and provide written informed consent. Exclusion Criteria: * Presence of cardiovascular diseases other than hypertension. * Neurological disorders. * Psychiatric disorders. * Orthopedic conditions limiting participation in resistance exercise. * Any other systemic disease that may interfere with study participation. * Cognitive impairment or psychological conditions preventing completion of the assessments. * History of recent surgery or medical conditions contraindicating exercise. * Inability or unwillingness to comply with the study protocol.

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Conditions

The condition(s) this trial relates to.

hypertensive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Hypertension

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Munzur University Faculty of Health Sciences

    RECRUITING

    Tunceli, Turkey (Türkiye)

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