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One-Leg workouts beat Two-Leg training for ACL recovery

NCT ID NCT07271173

Symptom relief Sponsor: Peking University Third Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether doing strength exercises one leg at a time (unilateral training) helps people regain leg strength and balance better than using both legs together after ACL reconstruction surgery. 48 adults who had surgery at least 3 months ago completed 6 weeks of supervised training. The goal was to see which method leads to more equal strength between the injured and healthy leg.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

48 people

The number who actually took part.

Started

Apr 2025

Finished

Nov 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

30 to 55 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 30-55 years * ACLR performed with hamstring-tendon autograft ≥ 3 months ago * Full extension (no loss) and ≤ 5° difference in knee-flexion range between limbs, with flexion ≥ 120° * Able to recruit quadriceps adequately (no lag during 10 consecutive straight-leg raises on the involved side) * Can stand pain-free on the involved leg for ≥ 5 s without support * Has signed informed consent and can complete all study procedures Exclusion Criteria: * Previous lower-limb surgery on either leg, including revision ACLR * Any prior knee surgery on the contralateral limb * Associated ligament ruptures or fractures * Severe patellar chondral damage * Post-operative arthrofibrosis * Professional athletes * Cardiac disease * Pregnant or lactating women

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Anterior cruciate ligament reconstruction rehabilitation

Contacts and locations

Locations

  • Peking University Third Hospital of Chongli

    Zhangjiakou, Hebei, 076350, China

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