One-Legged treadmill training shows promise for stroke recovery
NCT ID NCT05449301
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether training one leg at a time on a treadmill improves walking and balance in stroke survivors more than standard two-legged training. 63 people who had an ischemic stroke at least 3 months prior took part. They did either unilateral step training, rhythmic auditory stimulation, or regular treadmill training for 12 weeks. The goal was to see if this targeted approach helps with gait, balance, and daily activities.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Unilateral step training on a treadmill
- What this could lead to
- If it works, this could offer a simple, targeted exercise to help stroke survivors walk better and reduce fall risk.
- What could go wrong
- This is a small, completed trial with 63 people, so results may not apply to all stroke patients. The training requires access to a treadmill and supervision.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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63 people
The number who actually took part.
- Started
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Jan 2023
- Finished
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Jun 2024
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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40 to 60 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Both Genders. 2. Age: 40-60 years 3. Ischemic stroke 4. Patients having stroke involving Middle Cerebral Artery 5. Patients in sub-acute (3 months) and chronic phase (6 months) of stroke 6. Mini-Mental State Exam score \> 24 7. Functional Ambulatory Capacity: 3-5 Exclusion Criteria: 1. Patients with unstable medical conditions (e.g., DVT, uncontrolled hypertension, uncontrolled diabetes and musculoskeletal injuries) 2. History of other diseases known to interfere with participation in the study (e.g., heart failure, epilepsy) 3. Participants with cognitive impairment. 4. Score of muscle tone on Modified Ashworth Scale: 3-4
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Foundation University College of Physical Therapy
Islamabad, 44000, Pakistan
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Other studies related to the condition(s) this trial covers.
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