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Can Water-Filled stomach surgery spare patients from scalpel?

NCT ID NCT07728292

Disease control Sponsor: Asian Institute of Gastroenterology, India Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 27, 2026 · Last updated Jul 28, 2026 · Updated 1 time

Summary

This trial tests whether a procedure called underwater endoscopic mucosal resection (UEMR) can safely and completely remove small type I gastric neuroendocrine tumors (5-9 mm). Instead of traditional surgery, doctors fill the stomach with saline and use a snare to cut out the growth while it floats. The study will check how often the tumor is removed with clean edges and track any complications or regrowth over time.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
underwater endoscopic mucosal resection (UEMR) — a procedure that removes small stomach tumors while the organ is filled with saline
What this could lead to
If successful, this technique could offer a less invasive, effective way to remove small stomach neuroendocrine tumors without surgery.
What could go wrong
This is a small, single-center study with only 60 participants. The procedure may not achieve complete tumor removal in all cases, and risks include bleeding or perforation.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 60 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jul 2026

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Patient-level * Age ≥18 years * Fit for endoscopic therapy and sedation * Written informed consent Exclusion Criteria: Lesion-level * Endoscopically visible gastric neuroendocrine tumor * Size 5-9 mm (endoscopic estimation) * Clinical and/or histologic features consistent with type I gastric NET * No endoscopic features suggestive of deep invasion * Technically amenable to snare resection

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Conditions

The condition(s) this trial relates to.

gastric neuroendocrine neoplasm gastric neuroendocrine tumor, well differentiated, low or intermediate grade

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Stomach neuroendocrine neoplasm

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Asian Institute of Gastroenterology/AIG Hospitals

    RECRUITING

    Hyderabad, Telangana, 500082, India