Scientists unmask bacterial evasion tactics in immune study
NCT ID NCT00339287
First seen Jun 27, 2026 · Last updated Sep 17, 2026 · Updated 13 times
Summary
This study aims to understand how certain bacteria avoid being killed by our immune cells, leading to infections. Researchers will collect blood samples from 200 healthy adults to study these interactions in the lab. The goal is to learn more about how bacteria cause disease and how our immune system responds, which could inform future treatments.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 200 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Feb 2001
- Lead sponsor
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A government research agency
The lead sponsor is the US National Institutes of Health.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Volunteers will be selected from a healthy adult population, 21-65 years of age, with no known medical problems and will generally be NIH employees working at Rocky Mountain Laboratories (RML) or within the community of Hamilton, MT. No race or gender is excluded from the donor pool and reflects the diversity of the community and that of the employees at RML.
- Ages
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18 to 120 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
* INCLUSION \& EXCLUSION CRITERIA: Volunteers will be selected from a healthy adult population, 18 years of age or older, with no known medical problems and will generally be NIH employees working at Rocky Mountain Laboratories (RML) or within the community of Hamilton, MT. No race or gender is excluded from the donor pool and reflects the diversity of the community and that of the employees at RML. The specific criteria for eligibility are as follows: * Subjects must fit the definition of "healthy adults" as assessed by the medical/health screening evaluations, and willing to have blood and/or tissue samples stored for future use. * Inasmuch as all subjects are RML employees, they will be 18 years of age or older. * Children are excluded. * Pregnant women will be identified by verbal history and are not eligible to donate blood for this protocol. * The study population will be all-inclusive except in certain instances where individuals possess genetic defects that impair phagocyte function (e.g., myeloperoxidase-deficiency) or have altered phagocyte function due to outside influences such as recent bacterial or viral infection. * Individuals below the normal hematocrit and hemoglobin ranges will be excluded from the protocol.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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NIAID, Rocky Mountain Laboratories
RECRUITINGHamilton, Montana, 59840, United States