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Brain scans reveal why dystonia patients feel out of control

NCT ID NCT03351218

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at how people with cervical or myoclonus dystonia perceive their own actions, known as the 'sense of agency.' Researchers used computer tasks and brain scans to measure how accurately participants felt in control of their movements. The goal was to link these feelings to brain structure and symptom severity.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this research could improve understanding of why some people with dystonia feel a lack of control over their movements, potentially guiding future therapies.
What could go wrong
This is an observational study, not a treatment trial. It aims to gather knowledge, not test a cure or therapy, so direct patient benefits are not expected.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

76 people

The number who actually took part.

Started

Oct 2017

Finished

Dec 2022

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

15 to 65 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * diagnosis of isolated adult-onset cervical dystonia (CD) or myoclonus dystonia (MD); * duration of disease of more than one year * no botulinum toxin injection for at least three months before the study * normal or corrected-to-normal vision. Exclusion Criteria * any neurological history except for dystonia, * history of dopamine antagonist treatment, * secondary dystonia, * dystonia in the upper limbs, * inability to maintain gaze straight.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Centre d'investigation Clinique

    Paris, Île-de-France Region, 75013, France

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Other studies related to the condition(s) this trial covers.