Can sound waves or nerve glides ease carpal tunnel pain?
NCT ID NCT07743879
First seen Aug 04, 2026 · Last updated Aug 05, 2026 · Updated 1 time
Summary
This trial tests whether ultrasound therapy, nerve gliding exercises, or a combination of both can reduce pain and improve hand function in people with mild-to-moderate carpal tunnel syndrome. Participants will be randomly assigned to one of three groups: ultrasound alone, nerve gliding alone, or both together. The study measures changes in pain intensity, symptom severity, and daily function to see which approach helps most.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Therapeutic ultrasound and median nerve neurodynamic mobilization (nerve gliding exercises), tested alone and in combination.
- What this could lead to
- If effective, this could point to a non-surgical way to ease pain and improve hand function in people with mild-to-moderate carpal tunnel syndrome.
- What could go wrong
- This is a small, early-stage trial, and results may not apply to everyone. Benefits, if any, may be modest, and some people may not respond to these therapies.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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60 people
The number who actually took part.
- Started
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Feb 2025
- Finished
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Nov 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Clinical diagnosis of mild to moderate carpal tunnel syndrome confirmed by electrophysiological testing. * Age between 18 and 65 years. * Presence of symptoms (pain, numbness, tingling) for at least 3 months. Exclusion Criteria: * History of previous carpal tunnel release surgery or wrist trauma. * Corticosteroid injection into the wrist within the past 3 months. * Cervical radiculopathy, polyneuropathy, or other upper extremity neurological disorders. * Pregnancy or lactation. * Contraindications to therapeutic ultrasound (e.g., active infection, metallic implants in the treatment area, malignant tumors).
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Ibb University
Ibb, nine, Yemen
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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