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Scientists use ultrasound to uncover muscle secrets behind common knee pain

NCT ID NCT07425340

Knowledge-focused Sponsor: Hasan Kalyoncu University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study will use ultrasound to examine two specific thigh muscles in people with patellofemoral pain syndrome (front knee pain) and compare them to healthy individuals. Researchers aim to better understand how these muscles differ in people with knee pain, which could lead to more targeted physical therapy. The study will involve 40 participants aged 18 to 65.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could help physical therapists design better muscle-specific exercises for knee pain.
What could go wrong
This is an observational study with only 40 participants, so results may not apply to everyone. It does not test a treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 40 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Feb 2026

An estimate. Start dates often move.

Expected to finish

Jun 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study will include individuals aged 18-65 who have been diagnosed with patellofemoral pain syndrome, as well as healthy volunteers with similar characteristics in terms of age and gender. The study group will consist of individuals who have applied to a physical therapy and rehabilitation clinic or who have been referred to relevant units. The control group will be selected from healthy volunteers who do not have any knee pain or lower extremity musculoskeletal problems.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Between the ages of 18 and 65 * Have had localized pain in the front of the knee for at least the past 3 months * Experience pain during activities that require stair climbing, squatting, prolonged sitting, or knee flexion * Have been diagnosed with patellofemoral pain syndrome based on clinical evaluation * Volunteer to participate in the study and sign the informed consent form Exclusion Criteria: * History of previous surgery on the knee joint * History of significant trauma to the knee region within the last 6 months * Diagnosis of meniscus, ligament injuries, knee osteoarthritis, or inflammatory rheumatic disease * Neurological diseases or systemic diseases affecting the musculoskeletal system * Presence of other lower extremity pathologies causing pain at a level that could affect measurements

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Conditions

The condition(s) this trial relates to.

patellofemoral pain syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Patello femoral pain syndrome Ultrasonographic Vastus medialis

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Hasan Kalyoncu University

    Gaziantep, Şahinbey, (505) 090-5846, Turkey (Türkiye)

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