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New nerve block could replace morphine for lung surgery pain

NCT ID NCT07330479

Symptom relief Sponsor: University of Gaziantep Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a new nerve block called SPSIPB for pain after video-assisted lung surgery. Sixty adults were randomly assigned to get either the nerve block or a morphine injection. The goal was to see which method provided better pain relief and reduced the need for extra painkillers.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Ultrasound-guided serratus posterior superior intercostal plane block (SPSIPB) with local anesthetic
What this could lead to
If it works, this could offer a safer, effective way to manage pain after lung surgery, reducing the need for strong painkillers like morphine.
What could go wrong
This is a small, early-stage study with only 60 patients. The block may not work better than morphine, and results may not apply to all surgeries or patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

60 people

The number who actually took part.

Started

Feb 2024

Finished

Aug 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 70 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Age between 18 and 70 years 2. American Society of Anesthesiologists (ASA) physical status I-III 3. Scheduled for elective video-assisted thoracoscopic surgery (VATS) under general anesthesia 4. Provision of written informed consent Exclusion Criteria: 1. Conversion to thoracotomy during surgery 2. Coagulopathy or ongoing anticoagulant therapy 3. Local infection at the injection site 4. Known allergy to local anesthetics or morphine 5. Severe cardiopulmonary disease contraindicating regional anesthesia 6. Refusal to participate in the study

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Postoperative pain, acute

Contacts and locations

Locations

  • Gaziantep University

    Gaziantep, 27410, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.