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Can a simple injection ease pain from brain surgery head gear?

NCT ID NCT07629713

First seen Jun 11, 2026 · Last updated Jun 19, 2026 · Updated 1 time

Summary

This study tested whether injecting lidocaine, a numbing medicine, at two different strengths (0.5% vs 1%) could reduce pain from the head holder used during brain surgery. 75 patients were split into two groups and received the injection before surgery. Researchers then compared their pain levels and how much extra painkiller they needed in the first 24 hours after surgery.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Kocaeli Üniversitesi Tıp Fakültesi Hastanesi

    Kocaeli, İzmit, 41100, Turkey (Türkiye)

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

lidocaine

What this could lead to

If successful, this could show that a simple lidocaine injection reduces pain from head holders during brain surgery, improving patient comfort.

What could go wrong

This is a small, completed Phase 4 study with only 75 participants. Results may not apply to all patients or surgeries, and lidocaine may not work for everyone.

Conditions

The condition(s) this trial relates to.

Pain, Postoperative Pituitary Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.