New injection technique may offer longer relief for piriformis pain
NCT ID NCT07326982
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares two treatments for buttock pain caused by piriformis syndrome and related muscle pain. Researchers will use ultrasound to guide either a sugar-water injection or a dry needle into the affected area. The goal is to see which method provides better pain relief over three months. The trial plans to enroll 42 adults aged 18 to 75.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 42 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Mar 2026
An estimate. Start dates often move.
- Expected to finish
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Sep 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 75 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults aged 18 to 75 years * Buttock pain with or without radiation to the lower extremity * Ability to understand and provide written informed consent Exclusion Criteria: * Active lumbar radiculopathy * History of hip joint pathology or prior hip surgery * Previous injection or dry needling treatment to the gluteal region within the last 3 months * Coagulation disorders or use of anticoagulant therapy * Pregnancy * Local infection at the injection site * Inability to complete the study protocol or attend follow-up visits.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Istanbul University-Cerrahpaşa, Cerrahpaşa Faculty of Medicine
Istanbul, Istanbul, Turkey (Türkiye)
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a fluid injection between muscle layers ease piriformis pain?
- Can targeted muscle techniques outperform standard therapy for piriformis pain?
- Flat feet may be tied to a common cause of hip pain, study suggests
- Massage vs stretch: which eases piriformis pain better?
- Gentle muscle moves may ease piriformis pain – which works best?
- Laser or shockwave: which eases piriformis pain best?