Massage vs stretch: which eases piriformis pain better?
NCT ID NCT07661485
First seen Jun 26, 2026 · Last updated Jul 01, 2026 · Updated 3 times
Summary
This study compares two manual therapy techniques—myofascial release and post-isometric relaxation—for treating piriformis syndrome, a condition where a muscle in the buttock presses on the sciatic nerve, causing pain, numbness, and tingling. Twenty-six adults aged 20 to 50 with moderate to severe pain will be randomly assigned to receive one of the two techniques over four weeks. Researchers will measure changes in pain and lower leg function to see which approach works better.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Manual therapy techniques: myofascial release and post-isometric relaxation
- What this could lead to
- If one technique works better, it could point toward a more effective physical therapy approach for piriformis syndrome pain and mobility.
- What could go wrong
- This is a very small trial (26 people) that hasn't started yet. Results may not apply to everyone, and the techniques may not differ in effectiveness.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 26 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jun 2026
An estimate. Start dates often move.
- Expected to finish
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Sep 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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20 to 50 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Positive Lasegue sign * Positive FAIR test * Grade 1-3 tenderness on palpation of piriformis between sacrum and greater trochanter of femur * 4 or more pain intensity on the VAS scale Exclusion Criteria: * Lower extremity injuries including ligament, tendon injuries, muscle strains as well as nerve injuries * Systemic diseases including tuberculosis, multiple sclerosis, Parkinson's disease as well as chronic inflammatory conditions * Congenital deformities including hip dysplasia, limb length discrepancy, scoliosis and congenital pelvic asymmetry * Cognitive issues including dementia, severe depression and severe psychotic disorders * Lumbar Radiculopathy * SIJ Dysfunction * Lower Extremity Fractures * Pregnancy * Malignancy
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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The University of Faisalabad
Faisalābad, Punjab Province, 38000, Pakistan
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can a simple tape boost sciatica recovery and balance?
- Shockwave or ultrasound? trial aims to settle which therapy eases sciatica pain and improves sleep