Throat cancer diagnosis could get faster and more accurate with new ultrasound technique
NCT ID NCT07548268
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether adding a special ultrasound of the tonsils to standard exams helps doctors diagnose oropharyngeal cancer more accurately. About 180 patients with suspected throat cancer will be randomly assigned to either standard diagnostics alone or standard diagnostics plus the ultrasound. Researchers will compare how often the correct diagnosis is made, how many biopsies are successful, and how quickly the diagnosis is reached.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- transoral and cervical ultrasound
- What this could lead to
- If successful, this could make diagnosing oropharyngeal cancer faster and more accurate, reducing the need for extra scans and repeat biopsies.
- What could go wrong
- This is a relatively small, early-stage study. The ultrasound technique may not prove consistently better than current methods, and results may not apply to all hospitals.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 180 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Aug 2025
- Expected to finish
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May 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Referred to outpatient cancer clinic with one of the following: * A scan (MR, CT, PET/CT) suggesting malignancy in the oropharynx. This being asymmetric metabolic activity on PET/CT, a tumor or asymmetry of the palatine and lingual tonsils on MR and CT (7). * Tumor suspicious findings (erosion/ulcus, tonsil asymmetry/hypertrophy). * Tumor-suspicious symptoms (pain of the oropharynx) * \> 18 years of age. * Ability to understand and give informed consent. Exclusion Criteria: * • Prior oropharyngeal cancer * Prior radiation to the head and neck area
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
4 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Department of ORL - Head & Neck Surgery and Audiology, Zealand University Hospital,
NOT_YET_RECRUITINGKøge, Denmark
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Department of Otorhinolaryngology, Head and Neck Surgery & Audiology
RECRUITINGCopenhagen, 2100, Denmark
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Department of Otorhinolaryngology, Head and Neck Surgery & Audiology Northzealand Hospital
NOT_YET_RECRUITINGHillerød, Denmark
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Department of Otorhinolaryngology, Head and Neck Surgery, Aarhus University Hospital
NOT_YET_RECRUITINGAarhus, Denmark
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