Ultrasound may guide gum surgery by revealing hidden blood vessels
NCT ID NCT07727707
First seen Jul 27, 2026 · Last updated Jul 28, 2026 · Updated 1 time
Summary
This study tests whether ultrasound can map blood vessels in the lower jaw before gum recession surgery. Four adults with gum recession will receive a coronally advanced flap procedure, and researchers will compare ultrasound images taken before surgery with what they see during and after the operation. The goal is to see if ultrasound can help predict bleeding and improve surgical planning.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could help surgeons plan gum recession procedures more precisely, potentially reducing complications.
- What could go wrong
- This is a very small case series with only 4 participants, so results may not apply broadly. The technique is exploratory and not yet proven to improve outcomes.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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4 people
The number who actually took part.
- Started
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Apr 2026
- Finished
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Jun 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Potential participants will be identified and recruited during participant consultations at the department of periodontology. No additional recruitment material (such as for example flyers, social media advertising, audio/video recordings) will be used.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Age ≥ 18 years. 2. Presence of at least one mandibular gingival recession defect (RT1 or RT2) at an anterior, canine, or premolar tooth with an indication for treatment using a coronally advanced flap (CAF). 3. Good oral hygiene: full-mouth plaque score (FMPS) ≤ 20% and full-mouth bleeding score (FMBS) ≤ 20%. 4. Periodontal stability: no active or untreated periodontitis; probing depths ≤ 4 mm at the study site. 5. Ability to undergo pre-operative and post-operative ultrasound imaging and clinical documentation. 6. No contraindication to local anaesthesia or minor periodontal surgery. 7. Ability and willingness to comply with all scheduled follow-up visits (days 7, 14, 30 and 4 months). 8. Provision of written informed consent prior to any study-related procedures. Exclusion Criteria: 1. Systemic contraindications to minor oral surgery (ASA ≥ III, uncontrolled diabetes mellitus \[HbA1c \> 7.5%\], immunosuppressive therapy, bleeding disorders, or coagulation abnormalities). 2. Current antithrombotic therapy that cannot be safely managed peri-operatively according to the treating clinician. 3. Smoking more than 10 cigarettes per day or equivalent vaping within the previous 6 months. 4. Previous mucogingival surgery, traumatic scarring, or soft-tissue grafting in the mandibular anterior or premolar region that could interfere with vascular assessment. 5. Active oral infection or acute gingival inflammation at or near the study site. 6. Untreated caries, endodontic pathology, or restorative defects at the involved tooth. 7. Pregnancy or lactation. 8. Known allergy or hypersensitivity to ultrasound gel or (if applied) indocyanine green (ICG) or iodine. 9. Liver dysfunction or other medical contraindication precluding ICG use (relevant only if optional perfusion imaging is performed). 10. Inability or unwillingness to comply with study procedures or follow-up schedule.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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UZLeuven, Campus St. Raphaël, Department Oral Health Sciences, Periodontology
Leuven, Vlaams Brabant, 3000, Belgium
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