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Ultrasound may guide gum surgery by revealing hidden blood vessels

NCT ID NCT07727707

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 27, 2026 · Last updated Jul 28, 2026 · Updated 1 time

Summary

This study tests whether ultrasound can map blood vessels in the lower jaw before gum recession surgery. Four adults with gum recession will receive a coronally advanced flap procedure, and researchers will compare ultrasound images taken before surgery with what they see during and after the operation. The goal is to see if ultrasound can help predict bleeding and improve surgical planning.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could help surgeons plan gum recession procedures more precisely, potentially reducing complications.
What could go wrong
This is a very small case series with only 4 participants, so results may not apply broadly. The technique is exploratory and not yet proven to improve outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

4 people

The number who actually took part.

Started

Apr 2026

Finished

Jun 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Potential participants will be identified and recruited during participant consultations at the department of periodontology. No additional recruitment material (such as for example flyers, social media advertising, audio/video recordings) will be used.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Age ≥ 18 years. 2. Presence of at least one mandibular gingival recession defect (RT1 or RT2) at an anterior, canine, or premolar tooth with an indication for treatment using a coronally advanced flap (CAF). 3. Good oral hygiene: full-mouth plaque score (FMPS) ≤ 20% and full-mouth bleeding score (FMBS) ≤ 20%. 4. Periodontal stability: no active or untreated periodontitis; probing depths ≤ 4 mm at the study site. 5. Ability to undergo pre-operative and post-operative ultrasound imaging and clinical documentation. 6. No contraindication to local anaesthesia or minor periodontal surgery. 7. Ability and willingness to comply with all scheduled follow-up visits (days 7, 14, 30 and 4 months). 8. Provision of written informed consent prior to any study-related procedures. Exclusion Criteria: 1. Systemic contraindications to minor oral surgery (ASA ≥ III, uncontrolled diabetes mellitus \[HbA1c \> 7.5%\], immunosuppressive therapy, bleeding disorders, or coagulation abnormalities). 2. Current antithrombotic therapy that cannot be safely managed peri-operatively according to the treating clinician. 3. Smoking more than 10 cigarettes per day or equivalent vaping within the previous 6 months. 4. Previous mucogingival surgery, traumatic scarring, or soft-tissue grafting in the mandibular anterior or premolar region that could interfere with vascular assessment. 5. Active oral infection or acute gingival inflammation at or near the study site. 6. Untreated caries, endodontic pathology, or restorative defects at the involved tooth. 7. Pregnancy or lactation. 8. Known allergy or hypersensitivity to ultrasound gel or (if applied) indocyanine green (ICG) or iodine. 9. Liver dysfunction or other medical contraindication precluding ICG use (relevant only if optional perfusion imaging is performed). 10. Inability or unwillingness to comply with study procedures or follow-up schedule.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • UZLeuven, Campus St. Raphaël, Department Oral Health Sciences, Periodontology

    Leuven, Vlaams Brabant, 3000, Belgium

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