Sound waves aimed at liver and nerves could tame diabetes
NCT ID NCT05354947
First seen Feb 02, 2026 · Last updated Jun 23, 2026 · Updated 22 times
Summary
This early study tests whether delivering focused ultrasound pulses to the liver and a nearby nerve bundle can improve blood sugar control in people with type 2 diabetes. Thirty adults on stable oral diabetes medications will receive the ultrasound treatment. The main goal is to check for side effects like liver enzyme changes, but researchers will also monitor blood sugar levels to see if the approach shows promise.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Yale-New Haven Hospital
RECRUITINGNew Haven, Connecticut, 06510, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
focused pulsed ultrasound delivered via a GE LOGIQ E10 machine
What this could lead to
If it works, this could point toward a non-drug, non-invasive way to help manage blood sugar in type 2 diabetes.
What could go wrong
This is a very early, small pilot study (30 people) focused on safety, not effectiveness. It may not show any meaningful blood sugar improvement, and there is a risk of liver enzyme elevation or low blood sugar.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.