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Study reveals how junk food rewires young brains

NCT ID NCT05550818

Knowledge-focused Sponsor: Virginia Polytechnic Institute and State University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Sep 09, 2026 · Updated 2 times

Summary

This study explored how eating a diet high in ultra-processed foods (like chips and sugary snacks) changes brain activity related to reward and leads to overeating. Researchers compared two diets in 36 adults aged 18-25. The goal was to understand, not treat, how these foods affect eating behavior.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

36 people

The number who actually took part.

Started

Mar 2023

Finished

Jun 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 25 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 18-25 years * Weight stable (+5 lbs) for previous 6 months * No plans to gain/lose weight or change physical activity level * Willing to pick up food daily and consume foods provided for two 14-day periods * Verbal and written informed consent * Unrestrained eater (TFEQ cognitive restraint score \<11) * No reported history of eating disorders * Sedentary to recreationally active * ADHD medications if same med \>3 months at time of study Exclusion Criteria: * BMI \>30 kg/m2 * Endocrine disorders or other major chronic disease (e.g., type 2 diabetes, hypothyroidism, hypertension) * Pregnant or plans to become pregnant * Food allergies or aversions * Claustrophobia * History of head injury with loss of consciousness for more than 10 minutes * Contraindications to MRI: individuals with pacemaker, aneurysm clips, neurostimulators, cochlear implants, metal in eyes, steel worker, or other implants.

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Conditions

The condition(s) this trial relates to.

Feeding Behavior

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Eating behavior Eating habit

Contacts and locations

Locations

  • Fralin Biomedical Research Institute at VTC

    Roanoke, Virginia, 24016, United States

  • Virginia Polytechnic Institute and State University

    Blacksburg, Virginia, 24061, United States

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