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Cord stem cells could tame lupus in early trial

NCT ID NCT06737380

First seen Nov 01, 2025 · Last updated Jun 23, 2026 · Updated 33 times

Summary

This early study tests whether a single injection of stem cells from donated umbilical cords is safe for people with active lupus. Ten adults will receive the cells plus their usual care. Researchers will monitor side effects and check if the treatment improves kidney function and reduces disease activity.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Medical University of South Carolina

    RECRUITING

    Charleston, South Carolina, 29425, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

umbilical cord-derived mesenchymal stromal cells (UC-MSCs)

What this could lead to

If this works, it could point toward a new treatment option for lupus that helps control the disease and protect kidney function.

What could go wrong

This is a very early Phase 1 trial with only 10 people, so it is mainly checking safety, not effectiveness. The treatment may not work or could cause side effects.

Conditions

The condition(s) this trial relates to.

systemic lupus erythematosus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.