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New drug cocktail targets Hard-to-Treat lung cancer

NCT ID NCT07463677

First seen Mar 13, 2026 · Last updated Jun 19, 2026 · Updated 15 times

Summary

This Phase 2 trial tests a combination of two drugs, tunlametinib and cetuximab β, in 55 people with advanced non-small cell lung cancer that has a KRAS mutation and has not responded to prior treatments. The goal is to see if the combo can shrink tumors and control the disease. The study is not yet recruiting.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Tunlametinib and Cetuximab β

What this could lead to

If successful, this combination could offer a new treatment option for people with a specific type of advanced lung cancer that has not responded to other therapies.

What could go wrong

This is an early Phase 2 trial with only 55 participants, so results may not apply to everyone. The combination may cause side effects or fail to shrink tumors.

Conditions

The condition(s) this trial relates to.

lung cancer lung neoplasm non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.