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New drug combo shows promise in aggressive lymphoma trial

NCT ID NCT04231448

First seen May 15, 2026 · Last updated May 22, 2026 · Updated 1 time

Summary

This phase 3 trial tested adding the drug tucidinostat to standard chemotherapy (R-CHOP) in 423 adults with a fast-growing type of lymphoma called double-expressor DLBCL. The goal was to see if the combination could delay the cancer from coming back or getting worse. Participants took either tucidinostat or a placebo pill along with their chemo, and researchers tracked how long they stayed cancer-free.

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Contacts and locations

Locations

  • Peking University Cancer Hospital

    Beijing, Beijing Municipality, China

  • Shanghai JiaoTong University School of Medicine,Ruijin Hospital

    Shanghai, Shanghai Municipality, China

Conditions

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