New drug combo shows promise for hard-to-treat lymphoma

NCT ID NCT04231448

First seen May 15, 2026 · Last updated May 15, 2026

Summary

This study tested whether adding an oral drug called tucidinostat to standard chemotherapy (R-CHOP) helps people with a fast-growing type of lymphoma called double-expressor DLBCL. The trial involved 423 newly diagnosed adults and measured how long they lived without the cancer getting worse. While the treatment aims to control the disease, patients may still need ongoing monitoring or future therapy.

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Contacts and locations

Locations

  • Peking University Cancer Hospital

    Beijing, Beijing Municipality, China

  • Shanghai JiaoTong University School of Medicine,Ruijin Hospital

    Shanghai, Shanghai Municipality, China

Conditions

Explore the condition pages connected to this study.