New hope for breast cancer patients with rare brain and spine spread
NCT ID NCT06016387
First seen Jan 31, 2026 · Last updated May 23, 2026 · Updated 12 times
Summary
This study tests whether combining targeted drugs (tucatinib, trastuzumab, and capecitabine) with radiation to the brain and/or spine is safe and effective for people with HER2-positive breast cancer that has spread to the lining of the brain and spinal cord (leptomeningeal disease). About 30 participants will receive radiation first, then the drug combination. The goal is to see if this approach can help control the disease and improve survival.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Sunnybrook Health Sciences Centre
RECRUITINGToronto, Ontario, M4N 3M5, Canada
Contact
Contact Email: •••••@•••••
Contact
Contact Email: •••••@•••••
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The Ottawa Hospital
RECRUITINGOttawa, Ontario, Canada
Contact Email: •••••@•••••
Conditions
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