Laser or wait? landmark trial tackles twin pregnancy dilemma
NCT ID NCT01220011
First seen Feb 17, 2026 · Last updated Apr 29, 2026 · Updated 12 times
Summary
This study looked at two approaches for managing stage 1 twin-to-twin transfusion syndrome (TTTS), a serious pregnancy condition where blood flow is uneven between twins. Researchers compared immediate laser surgery with careful monitoring (watchful waiting) in 179 pregnant women. The goal was to see which strategy leads to better survival and brain development for the babies at 6 months old.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Children's Hospital Colorado and Colorado Fetal Care Center
Aurora, Colorado, 80045, United States
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Fetal Care Center of Cincinnati, Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio, 45229-3026, United States
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Fetal Diagnosis and Treatment, The Children's Hospital of Philadelphia
Philadelphia, Pennsylvania, 19104, United States
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Fetal Therapy Program, Evergrenn Hospital Medical Center
Kirkland, Washington, 98034, United States
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Fetal Treatment Program of New England, Hasbro Children's Hospital, The Warren Alpert Medical School of Brown University.
Providence, Rhode Island, 02903, United States
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Hospital Ste-Justine
Montreal, Quebec, H3T 1R2, Canada
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Mount Sinai Hospital, University of Toronto
Toronto, Ontario, ON M5X 1X5, Canada
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Necker Enfants Malades
Paris, 75006, France
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The Ohio State University / OSU Fetal Therapy Program
Columbus, Ohio, 43221, United States
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The Texas Fetal Center, Children's Memorial Hermann Hospital, University of Texas Medical School
Houston, Texas, 77030, United States
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University of MD /Department of Obstetrics, Gynecology & Reproductive Sciences
Baltimore, Maryland, 21000, United States
Conditions
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