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Shock therapy for cramps? tiny trial tests nerve zaps for period pain

NCT ID NCT07352982

Symptom relief Sponsor: Kafrelsheikh University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a non-invasive nerve stimulation technique, called transcutaneous tibial nerve stimulation (TTNS), can reduce pain and improve quality of life in women with primary dysmenorrhea (painful periods). Thirty-two women aged 20-25 will receive either TTNS plus standard painkillers or a placebo version plus painkillers for three sessions a week over four weeks. The goal is to see if adding TTNS leads to greater pain relief and lower prostaglandin levels.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
transcutaneous tibial nerve stimulation (TTNS) plus nonsteroidal anti-inflammatory drugs
What this could lead to
If it works, this could offer a drug-free add-on option to ease period pain and improve daily life for women with primary dysmenorrhea.
What could go wrong
This is a small, early-phase study with only 32 participants, so results may not apply widely. The nerve stimulation is non-invasive, but the placebo group also gets standard painkillers, making it hard to separate the added benefit.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 32 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2026

Expected to finish

Jul 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 to 25 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age ranges from 20-25 years old. * Body mass index (BMI) doesn't exceed 30 kg/m2. * Patients referred from a Gynecologist with a diagnosis of Primary Dysmenorrhea (PD). * Patients have regular menstrual cycles. * Patients suffer from pain located in the suprapubic area, abdomen, lower lumbar area, perineum, and/or medial aspect of the thighs during at least half of their annual menstrual cycles and/or in the last 3 cycles. Exclusion Criteria: * Patients diagnosed with gynecological pathology. * Patients taking oral contraceptives or had an intrauterine device implanted. * Patients had bad obstetric situations or diseases that could interfere with participation. * Patients have certain disorders including uncorrected coagulopathies, severe comorbid disorder, cancer in the last 5 years or at present, presence of erosions on the inner aspect of the ankle, severe mental disorders, or neuropathies affecting the lower limb. * Patients who are smoking or taking oral sedatives. * Patients had undergone surgery or childbirth in the last 6 months. * Patients who are pregnant.

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Conditions

The condition(s) this trial relates to.

primary dysmenorrhea

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Primary dysmenorrhea Transcutaneous tibial nerve stimulation Women

How to take part

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  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

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Contacts and locations

Locations

  • Kafrelsheikh University (Faculty of Physical Therapy)

    RECRUITING

    Kafr ash Shaykh, Kafrelsheikh, 33516, Egypt

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