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Could a simple ankle zap ease overactive bladder?
NCT ID NCT05977634
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a device that sends mild electrical pulses to a nerve in the ankle (transcutaneous tibial nerve stimulation) can reduce overactive bladder symptoms and improve quality of life in women. Twenty-six women with idiopathic overactive bladder will receive the stimulation twice a week for six weeks, plus bladder training. Researchers will measure changes in urination frequency and symptom severity using questionnaires and bladder diaries.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Transcutaneous tibial nerve stimulation (a device that sends mild electrical pulses to a nerve in the ankle)
- What this could lead to
- If it works, this could offer a non-drug, non-surgical option to help women with overactive bladder control their symptoms and improve daily life.
- What could go wrong
- This is a very small study (26 people) with no placebo group, so results may not be reliable or apply to everyone. The treatment requires multiple clinic visits and may not work for all.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 26 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Sep 2023
- Expected to finish
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Aug 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 70 years
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Overactive Bladder Questionnaire Validation Study questionnaire 8 scores higher than 11. * Post voiding residue levels less than 100 ml. * Women aged between 18-70 Exclusion Criteria: * Prior history of pelvic surgery * Pelvic organ prolapsus of grade 2 or more. * Current urinary tract infection
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Ege University School of Medicine
Bornova, İzmir, 35100, Turkey (Türkiye)
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can a nerve pacemaker that takes breaks still tame an overactive bladder?
- Diabetes drug class may change how the bladder behaves
- Botox vs. blood plasma: which works better for a bladder that Won't quit?
- Vibrating device aims to restore bladder control in cancer survivors
- Ankle nerve zap may ease Kids' bladder troubles