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Zapping the brain to curb alcohol cravings: new trial underway

NCT ID NCT07472673

First seen Mar 23, 2026 · Last updated Jun 19, 2026 · Updated 12 times

Summary

This study tests a non-invasive brain stimulation technique called transcranial temporal interference stimulation (tTIS) aimed at the amygdala, a brain region linked to cravings. Researchers will enroll 60 adults with alcohol use disorder to see if tTIS can reduce alcohol cravings and prevent relapse. The approach uses two pairs of electrodes on the scalp to create a low-frequency electric field deep in the brain without surgery.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Shanghai Mental Health Center

    Shanghai, 200000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

transcranial temporal interference stimulation (tTIS) device

What this could lead to

If it works, this could offer a new, non-drug way to reduce alcohol cravings and help prevent relapse in people with alcohol use disorder.

What could go wrong

This is an early-stage study with only 60 participants, so results may not apply to everyone. The technique is experimental and its long-term effects are unknown.

Conditions

The condition(s) this trial relates to.

alcohol abuse

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.