New knee shot aims to ease arthritis pain in severe cases
NCT ID NCT05079035
First seen Nov 01, 2025 · Last updated May 20, 2026 · Updated 30 times
Summary
This study tested a single injection of TTAX03 in the knee for people with severe osteoarthritis (grades 3-4). 90 adults received either the study drug or a placebo (saline). The goal was to see if more people reported significant pain relief or better function after 12 weeks. The trial is now complete.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Alabama Orthopaedic Center
Birmingham, Alabama, 35243, United States
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Gulfcoast Research Institute
Sarasota, Florida, 34232, United States
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Horizon Clinical Research
La Mesa, California, 91942, United States
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Manage Sites/The Ohio State University Wexner Medical Center, Sports Medicine The Ohio State University Wexner Medical Center, Sports Medicine
Columbus, Ohio, 43201, United States
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Ochsner Health Center
Jefferson, Louisiana, 70121, United States
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Paragon Sports Medicine
Atlanta, Georgia, 30327, United States
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Precision Clinical Research
Sunrise, Florida, 33351, United States
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Rothman Orthopaedic Institute
Media, Pennsylvania, 19063, United States
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Tuscon Orthopedic Institute
Tucson, Arizona, 85712, United States
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UAB Orthopaedic Surgery
Birmingham, Alabama, 35205, United States
Conditions
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