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Pregnancy diet mystery solved? scientists pinpoint tryptophan needs

NCT ID NCT06519071

Knowledge-focused Sponsor: University of British Columbia Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study looked at how much tryptophan (an amino acid found in food) healthy pregnant women need. Researchers used a safe, noninvasive method with a special tracer to measure it in breath and urine. The goal is to improve dietary guidelines for pregnancy.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
tryptophan (amino acid) in liquid meals
What this could lead to
If successful, this could help set better dietary recommendations for tryptophan during pregnancy.
What could go wrong
This is a small, completed study with only 29 participants. Results may not apply to all pregnant women or change guidelines directly.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

29 people

The number who actually took part.

Started

Jul 2023

Finished

Jul 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 to 40 years

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Cis-gendered pregnant woman. * 20-40 years of age. * Pregnant with a single child. * Between 11-20 weeks of gestation or 31-40 weeks of gestation. * Free of chronic diseases/acute diseases and have a full range of physical mobility. Exclusion Criteria: * Women who are not pregnant. * Women who are pregnant with more than one child (this changes amino acid demands) or were pregnant in the 6 months before the current pregnancy. * Women with a history of spontaneous abortion (within the last 6 months) or preterm birth. * Women not in good health or have a metabolic, cardiovascular, neurological, genetic, or immune disorder, including gestational diabetes, preeclampsia, pregnancy-related anemia, or pregnancy-related jaundice. * Claustrophobic women (a clear hood will be placed, which can easily be removed, over the participants head for approximately 20 min to measure energy expenditure). * Women who are substance dependent (i.e., alcohol, tobacco, illicit drugs). * Women who have severe nausea/vomiting throughout their pregnancy. * Women under the age of 20 years and over the age of 40 years. * Women who have lost weight (approximately 1.5kg or more) during their current pregnancy. * Women with a pre-pregnancy Body Mass Index (BMI) under 19 or over 28 〖kg/m〗\^2.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Pregnancy

Contacts and locations

Locations

  • BC Children's Hospital Research Institute, University of British Columbia

    Vancouver, British Columbia, V5Z4H4, Canada

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